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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
21.21
Human Site:
S500
Identified Species:
33.33
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S500
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S500
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
T252
D
L
Y
D
L
G
S
T
S
V
Q
Q
W
P
A
Dog
Lupus familis
XP_534537
1097
121903
G487
V
P
A
P
T
P
S
G
A
E
G
L
D
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S499
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
S491
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Chicken
Gallus gallus
XP_419666
1136
127431
S506
P
I
Q
Q
P
V
K
S
M
R
V
L
K
P
E
Frog
Xenopus laevis
NP_001087838
1118
125984
R495
Q
Q
P
V
K
S
I
R
V
L
K
P
E
L
Q
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
S486
A
P
A
A
E
V
P
S
Y
Q
G
P
P
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Q489
Q
Q
Q
Q
Q
Q
V
Q
Q
Q
Q
V
Q
Q
Q
Honey Bee
Apis mellifera
XP_395146
1137
124999
S536
G
T
A
T
T
E
D
S
N
C
I
S
T
I
D
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
L576
V
E
M
K
T
K
D
L
H
L
K
V
P
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q199
Q
Q
E
Q
E
N
V
Q
V
Q
Q
Q
L
S
Q
Red Bread Mold
Neurospora crassa
P38679
598
67999
Q41
Q
P
V
F
P
G
Q
Q
A
G
G
S
Q
Q
Y
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
6.6
6.6
N.A.
100
N.A.
N.A.
100
100
0
20
N.A.
13.3
6.6
0
0
P-Site Similarity:
100
100
20
13.3
N.A.
100
N.A.
N.A.
100
100
20
26.6
N.A.
40
20
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
20
7
0
0
0
0
14
0
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
14
0
0
0
0
0
7
0
7
% D
% Glu:
0
7
7
0
14
7
0
0
0
7
0
0
7
0
34
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
14
0
7
0
7
20
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
0
0
7
0
0
0
7
0
0
7
0
% I
% Lys:
0
0
0
7
7
7
34
0
0
0
14
0
34
0
7
% K
% Leu:
0
7
0
0
7
0
0
7
0
14
0
40
7
7
0
% L
% Met:
0
0
7
0
0
0
0
0
34
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% N
% Pro:
34
20
7
7
40
7
7
0
0
0
0
14
14
47
14
% P
% Gln:
27
20
40
47
7
7
7
20
7
20
20
14
14
14
20
% Q
% Arg:
0
0
0
0
0
0
0
7
0
34
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
14
47
7
0
0
14
0
7
0
% S
% Thr:
0
7
0
7
20
0
0
7
0
0
0
0
7
0
0
% T
% Val:
14
0
7
7
0
40
14
0
14
7
34
14
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _